Stem Cell Term Paper

5531 words - 23 pages

An Analysis of the
Emerging U.S Stem Cell Industry
Management of Technology - MGMT 620 (EMBA)
Professor – Dr. Gopalakrishnan

Norman Cousar
Draft Version 3
December 16, 2011

Due to previous government regulations, US companies have not used embryos for stem cell research, and international companies have gained a first mover advantage in commercializing stem cell treatments and therapies.
The use of stem cells has opened up a new field called regenerative medicine or cell therapy, which replaces damaged or diseased cells that are in the body with new ones. Stem cells have the ability to develop into many different cell types within the body during the early life and growth cycle. ...view middle of the document...

The advancement of stem cells in the biological science field has brought new hope for the treatment of Parkinson’s and heart diseases.
Human embryonic stem cells (hESCs) that are derived from the inner cell mass of a blastocyst, 4-5 days after fertilization. They are the most pluripotent of all stem cell types and can develop into over 200 different cell types of the human body, providing tremendous therapeutic potential. The first stem cell (hESC) was first derived from a mouse embryos in 1981.In 1995, the first successful culturing of primate embryonic stem cell occurred, at the University of Wisconsin-Madison. In 1998 another breakthrough occurred with Dr. James Thomson, who developed a technique to isolate and grow human embryonic stem cells.
As a result of these significant accomplishments at the University of Wisconsin, the Wisconsin Alumni Research Foundation (WARF) filed a series of landmark patents that have has affected the intellectual property landscape ever since. The “composition of matter” patents, that they filed concerning embryonic stem cells were so broad in nature, that they covered all human embryonic stem cell lines in the United States, not just the specific stem cell lines that were developed by James Thompson.

Since then, the WARF has been the major “gatekeeper”, determining which research product companies are allowed to conduct research and create commercial products using hESCs. WARF has also controlled what pharmaceutical companies have been allowed to develop hESC therapies. Since obtaining its landmark patents in 1998, WARF has only entered into licensing agreements with only 27 commercial partners for its intellectual portfolio related to isolating and differentiating hESCs. They have also agreed to allow 300 academic laboratories to use the technology without charge.

The low number of licensing agreements suggests that many companies find WARF’s licensing fees to be unwieldy, ranging between $75,000 and $250,000, plus annual payments and royalties. Consequently many other research product companies, have had to explore less costly alternatives to develop stem cells - such as conducting research off-shore, developing embryonic stem cell products for other species, and pursuing strategic collaborations.

Current research indicates that stem cell therapies have immense market potential driven by strong pipeline that caters to high unmet needs. Increasing investment and supportive regulatory environment in key geographies will help the stem cells industry to realize its full potential. Stem cell therapies high market potential is based on their unique ability to offer curative treatment in comparison to the symptomatic treatment offered by conventional treatments.
From a commercial perspective, many diseases arise as a result of irreversible damage to specialized cell types that cannot be served based on conventional pharmaceutical and biotech research. Not serving these diseases has resulted in...

Other Papers Like Stem Cell Term Paper

Stem Cell Research: What Is It? A Paper For A Communication And Gender Class, Overview Of Topic And Ethical Concerns

1448 words - 6 pages With all the media coverage on stem cell research during the past election, one would think that the general public had all of the information on stem cell research. This is not the case, however. Most people believe that stem cells are cells that must be extracted from a human embryo in order to do any good in the medical community, which is only partly true. Based solely on this information, armed with religious and ethical arguments, many

Stem Cell Therapy Essay

5775 words - 24 pages [pic] Term paper Stem cell therapy Irfan manzoor. Roll no: RP7002B22. Reg. no: 11000225. Course: Bsc. Biotech 1. Lovely professional university Contents 1. Stem

The Scientific and Political Advantages of Embryonic Stem Cell Research

2604 words - 11 pages Katie Wayne 4th Period Economics Honors Silton Term Paper The Scientific and Political Advantages of Embryonic Stem Cell Research There are over two hundred different kinds of cells in the human body that can all be traced back to the pool of stem cells in the embryo. During early development and even later on in life these stem cells can become specified cells that carry out different functions in the human body. The two types

Aarkstore - PharmaSphere: Emerging Biotechnologies - Stem Cell Therapy

4711 words - 19 pages & Development 213 8.4.6 Total Operating Expense 214 8.4.7 Operating Income 215 8.4.8 Provision for Taxes 216 8.4.9 Net Income 217 8.4.10 Cash and Short-Term Investments 218 8.4.11 Net Property/Plants/Equipment 219 8.4.12 Long-Term Investments 220 8.4.13 Long-Term Debt 221 8.4.14 Total Debt 222 8.4.15 Debt-to-Equity Ratio 223 8.4.16 Cash Ratio 224 8.4.17 Market Capitalization 225 9 Strategic Outlook 227 9.1 Stem Cell Industry Challenges

Stem Cell Research

1066 words - 5 pages point in life, including the embryonic stage of development. Many oppose federal funding of embryo- killing research on pragmatic grounds, arguing that ethical adult stem-cell research is already treating more than 70 diseases, which offers far more promise for near-term therapies for patients. The unproven promise of embryonic stem cell lies in their pliability; researchers hope they can be manipulated into becoming cells found in any part of

Pushing Medicine Into The Future

1523 words - 7 pages cloned cells with strains of DNA and same genetic makeup, no it will not. “The primary roles of adult stem cells in a living organism are to maintain and repair the tissue in which they are found. Scientists also use the term Somatic stem cell instead of adult stem cell, where Somatic refers to cells of the body (not the germ cells, sperm or eggs)” (IV. What are adult stem cells?). The adult and somatic stem cells are cells pulled from the recipient

Genetic Engineering

2349 words - 10 pages The Science and Ethics of Genetic Engineering Research & Position Paper Table of Contents DNA Fingerprinting/ Genetically Modified Foods --------------------------------------------------- p. 3 Gene Therapy/Cloning------------------------------------------------------------------------------------ p. 4 Stem Cell Technology------------------------------------------------------------------------------------ p. 5 Position Paper

Stem Cell Research 13

1788 words - 8 pages next presidential term of President George W. Bush from 2001-2009, who while campaigning made a speech declaring his opposition on embryonic stem cell research. Then on January 20, 2009, current president, Barack Obama, was sworn in as the 44th president of the United States. Having promised to change the current restrictions on human embryonic stem cell research, he issued an executive order on March 9, 2009 removing barriers for responsible

Stem Cell Research

1594 words - 7 pages of lives in the future. Right after the eruption of stem cell research, there was a new President taking office that did not have the same beliefs as Clinton did about the issue. The issue of stem cell research became a high-profile political issue in the U.S. during the first year of President George W. Bush's term in office in 2001. Avoiding the topic of banning funding for quite some time, Bush eventually enacted a ban on federal spending

The Great Debate Over Stem Cells Research

2199 words - 9 pages AbstractEmbryonic stem cells are controversial. They come from the inner cell mass of a blastocyst, the term for a fertilized egg four days after conception. But while many pro-life advocates stand firm in their opposition to using embryonic cells for research, others, have cast their lot with the scientific community in favor of continuing research funding (Varmus, 1998).Embryonic Stem Cells HistoryStem cell research is a complicated subject

Is Stem Cell Research Ethical

2560 words - 11 pages divide. The embryo created now has the patients’ genetics which decreases the possibility of rejection “In addition, it may be possible to learn more about the molecular causes of disease by studying embryonic stem cell lines from cloned embryos derived from the cells of animals or humans with different diseases” (genome.gov). However, this is another term for human cloning, which is legal but cannot be federally funded. Many states have laws in

Related Essays

Stem Cell Research Paper

1392 words - 6 pages Jean-Marie Lux Biology 121 Stem Cell Research Paper September 12, 2012 Stem cell research is a relatively new field and has made huge advances in the past fifty years. The idea of stem cells was first made public by a Russian-American Scientist named Alexander Maksimov in 1908. However it was not until 1963 that two Canadian Scientists were able to actually demonstrate the existence of self-renewing cells found in the bone marrow of mice

Stem Cell Debate Paper

1602 words - 7 pages Stemming Out: One Cell at a Time To every end there is a new beginning, but only if you allow it. Hundreds of thousands of patients could be saved at this very moment with a single cure but many question it. Stem cells have recently been discovered and have plenty of newfound helpful uses. From curing disease, to organ transplants and new limbs, and even cloning are possible with these simple cells. There are those who oppose it while claiming

Stem Cell Research Paper

1261 words - 6 pages ). To correct the disease, embryonic stem cells are injected into the eyes of patients in the hopes they will eventually replace the cells that are altering the vision. Mdsupport.org reports that the embryonic stem cells have shown encouraging signs of hope. In addition to embryonic stem cells there are also adult stem cells. Similarly to embryonic stem cells, they are able to transform into more than one type of cell, but adult stem cells are

Claim Paper Stem Cell Research

1939 words - 8 pages CLAIM: President Bush’s veto of the Stem Cell Research Enhancement Act in July of 2006 was a proportional reaction to the expanding influence of conservative political ideology and religious fundamentalism throughout America. VARIABLES: My independent variables are conservative political ideology and religious fundamentalism. My dependant variable is President Bush’s 2006 veto of the Stem Cell Enhancement Act, also known as the H.R. 810