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Ssri, The Cause Of Various Homicides

1912 words - 8 pages

April 20, 1999, began as an ordinary Tuesday morning in Littleton, Colorado for the students of Columbine High School who attended school unaware of the massacre that lay in their future. Two of the current students, Dylan Klebold and Eric Harris, would devastate a community, and open the eyes of the entire country. The boys killed twelve classmates and a teacher before taking their own lives in a similar manner. Additionally, nearly a year later in Boston, Massachusetts, an application support employee of Edgewater Technology, Michael McDermott, murdered seven of his co-workers with an AK-47, 12-gauge shotgun, and .32 caliber handgun. Surprisingly, he did not commit suicide like the ...view middle of the document...

Anti-depressants are drugs that encourage chemical changes that increase the amount of three neurotransmitters, which are serotonin, norepinephrine and dopamine. These are the three major neurotransmitters that are associated with mood in the brain. Neurotransmitters are the chemical messengers that carry a message throughout the body. The messages have information that regulates our body’s major functions like appetite, body temperature, behavior, and emotions. The neurotransmitter, or message carriers, are passed between the neurons ( When a neurotransmitter passes the message to the receiving neuron, the neurotransmitter is absorbed by a nerve/neuron to be recycled and reused. This recycling of the neurotransmitter is called reuptake (
When a patient suffers from depression, their natural levels of a neurotransmitter are very low. Therefore, the patient ingests an anti-depressant, the chemical in the pill stops the neuron from absorbing neurotransmitter which increases its levels. This is supposed to elevate the patient’s mood from a depressed state to a normal state, which takes an average of 30 days to become aware of effects ( Although Ann Blake Tracy Ph.D, Executive Director of the International Coalition for Drug Awareness, stated that, “elevated levels of serotonin is found in: psychosis or schizophrenia, mood disorders, organic brain disease, mental retardation, autism and Alzheimer's. While low levels of the metabolism of serotonin are found in those with: depression, anxiety, suicide, violence, and arson, substance abuse” ( A major type of anti-depressant, that has been connected to a plethora of massacres, is the selective serotonin reuptake inhibitors (SSRIs), which delays the reuptake of serotonin.
For example, when you are hungry, a message is sent on a neurotransmitter from the brain to stomach, using neurons, which creates your appetite. This process is similar to a train leaving the station in Harrisburg carrying passengers to another train station in Pittsburgh.
With this type of prescription drugs, the person is supposed to feel better in an almost euphoric state of mind, however the effects of the drug are variable. This variety depends on the differential body of its user. Some of the side-effects described by the firm and tested by the FDA aren’t seen in all of the patients, however these side effects are seen in a substantial amount for the side-effect to be listed on the label as a disclosure.
In 2004, the U.S. Food and Drug Administration ordered that anti-depressant manufacturers have a black-box warning, the FDA’s strongest warning, to notify the physicians of patients prescribed with SSRIs to attentively monitor their patients. This was due to a researched increased risk of suicidal thoughts and behavior in children and adolescents. Additionally, in 2006 the FDA extended this risk to adults in their late teens and early 20s....

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