Microbiology Essay

2628 words - 11 pages

Anti-Microbials and their source
Microorganism | Drug + additional notes |
Bacillus subtilis | Bacitracin: G(+), topical, nephrotoxic*doxycycline can be used for chronic renal disease*minocycline for acne & meningococcemia |
Bacillus polymyxa | Polymyxin |
Streptomyces nodosus | Amphotericin B |
Streptomyces noursei | Nystatin |
Streptomyces lincolnensis | Lincosamine |
Streptomyces orientalis | Vancomycin: for MRSA*Daptomycin for VRSA |
Streptomyces griseus | Streptomycin: vestibular toxicity w/ Gentamicin; 1st drug for TB |
Penicillium griseofulvum | Griseofulvin |

Gram (+) cocci arranged in clustersCatalase (+)Oxidase (-)Bacitracin-resistantLaboratory ...view middle of the document...

aureus, S. pyogenes) * cellulitis * necrotizing fasciitis * Non-suppurative * Toxin-mediated * scarlet fever (sand paper rash), * Streptococcal toxic shock-like syndrome (tampon) * Non-toxin mediated * Post-streptococcal glomerulonephritis immune complex depression kidney * Rheumatic heart fever (molecular mimicry): sore throat/ S pyogenes Ab developed vs. M protein; however M protein has lookalikes in heart valves, w/c are then attacked penicillin as prophylaxis | * Group B streptococcus * Neonatal sepsis and meningitis * Infection pag labas ng baby * vs Neonatal sepsis & food-born meningitis in L. monocytogenes | * Grow on bile esculin agar → black ppt * Reclassified under the genus Enterococcus * Enterococcus- assoc. as opportunistic pathogen * Group D & enterococci: * Diplococcic * α or γ hemolytic* Hemolysis * α → partial; green * β → complete; clear, white * γ → x hemolysis | * group of species * α or γ hemolytic * associated diseases: Streptococcus mutans * dental caries * bacterial endocarditis (biogenic heart valves) * intra-abdominal infections * bacteremia | * diplococcic, lancet-shaped, capsule * Quellung reaction → capsule swelling test * leading cause of Community Acquired Pneumonia (CAP) * 1st cause of Otitis Media * Sputum: bloody/ rusty colored * Prevention: pneumococcal conjugate vaccine* Quellung: Ab binds to capsule of: * S. pneumoniae * K. pneumoniae * N. meningitides * H. influenzae * E. coli * Salmonella |
*sidenote: Incidence = new cases; prevalence = new + old
3. Gram (-) coccobacilli |
Haemophilus influenza | Haemophilus aegyptius | Haemophilus parainfluenzae | Haemophilus ducreyi |
* forms * encapsulated: meningitis (most common for 5mos - 5y/o) * non-encapsulated: otitis media (2nd most common cause; 1st S. pneumoniae) * culture: Chocolate agar * prevention * Hib conjugate vaccine * Hyper immunoglobulin | * “Koch-weeks Bacillus” * Brazilian purpuric fever * Highly purulent conjunctivitis | * Bigger colonies in chocolate agar plate * Infective endocarditis | * Chancroid * Soft chancre * painfulvs. syphilis * Hard chancre * painless |
Bordetella pertussis |
* pearl-like colonies * metachromatic granules * Culture: Modified Bordet-Gengou agar * Pathogenicity * Pertussin toxin lymphocytosis * Hemagluttinin adherence * Tracheal cytotoxin damages; proliferation involves cilia | * Proliferation involves cilia * Whooping cough / pertussis * Via respiratory dropletsPrevention: DPT vaccine |
Brucella spp. |
* Catalase (+) * Oxidase (+) * Antigenic determinants * A antigen: Brucella abortus * M antigen: Brucella melitensis * Pathogenicity * Preference: fetal bovine tissue (because of erythritol) | ...

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