Gastric Bypass and Diabetes Literature Research
Grand Canyon University: NRS-433V Introduction to Nursing Research
Diabetes is one of the most deadly diseases known to man. That is a bold statement but when you consider that a big percentage of the other most deadly diseases like heart disease, kidney failure and strokes can be caused by diabetes then it puts it in to perspective. Diabetes causes many health problems besides these as well. The complications associated with diabetes are numerous but include neuropathy, blindness, amputation, impotency, depression and cognitive decline just to name a few. Some of these complications are inevitable ...view middle of the document...
It causes weight loss by restricting the amount of total caloric intake and has a secondary action of malabsorption. This has the effect of rapid weight loss rectifying many conditions caused by morbid obesity, one of these conditions being diabetes. Gastric bypass can reduce the symptoms of diabetes and in some cases cause total remission of the disease. Weight loss being the ultimate goal for treatment of diabetes and the direct result of gastric bypass makes it an answer to some patient’s prayers.
Hage, Mirella P.; Safadi, Bassem; Salti, Ibrahim; Nasrallah, Mona. Role of Gut-Related Peptides and Other Hormones in the Amelioration of Type 2 Diabetes after Roux-en-Y Gastric Bypass Surgery. ISRN Endocrinology (ISRN ENDOCRINOL), 2012; 1-13.
Bariatric surgery is currently the most effective and durable therapy for obesity. Roux-en-Y gastric bypass surgery, the most commonly performed procedure worldwide, causes substantial weight loss and improvement in several comorbidities associated with obesity, especially type 2 diabetes. Several mechanisms are proposed to explain the improvement in glucose metabolism after RYGB surgery: the caloric restriction and weight loss per se, the improvement in insulin resistance and beta cell function, and finally the alterations in the various gastrointestinal hormones and adipokines that have been shown to play an important role in glucose homeostasis. However, the timing, exact changes of these hormones, and the relative importance of these changes in the metabolic improvement postbariatric surgery remain to be further clarified. This paper reviews the various changes post-RYGB in adipokines and gut peptides in subjects with T2D.
García-Caballero, M., Valle, M., Martínez-Moreno, J., Miralles, F., Toval, J., Mata, J., & ... Mínguez, A. (2012). Resolution of diabetes mellitus and metabolic syndrome in normal weight 24-29 BMI patients with one anastomosis gastric bypass. Nutricion Hospitalaria, 27(2), 623-631 9p. doi:dx.doi.org/S0212-16112012000200041
Introduction: Diabetes mellitus type 2 (DMT2) is a major cause of death in the world. The medical therapy for this disease has had enormous progress, but it still leaves many patients exposed to the complications developed from the disease. It is well known the beneficial effects of bariatric surgery in obese diabetic patients, however it is important to investigate if the same principles of bariatric surgery that improve diabetes in obese patients, could be applied to non obese normal weight diabetics. Material and methods: Thirteen diabetic patients operated by One Anastomosis Gastric Bypass (BAGUA), were evaluated in the preoperative period and 1,3 and 6 months after surgery. Body weight and composition, Fasting Plasma Glucose, HbA1c levels, blood pressure and serum lipids levels were analyzed, as well as the monitoring of the immediate postoperative treatment necessities for Diabetes and other metabolic syndrome...