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Diabetes Essay

1778 words - 8 pages

There are many diseases that affect human beings all around the world. Some of these diseases are caused by people's diets, environment, or their heritage. My research is based on what causes diabetes and whether it is genetically predisposed.Before I get into the genetics of Diabetes I want to explain what it is. The article "Diabetes Explained" describes what it is by saying; "Diabetes (Diabetes Mellitus) is a severe, life-threatening condition in which the body loses its ability to turn glucose from food into usable energy." It is sometimes, mistakenly, called "Sugar" Diabetes because glucose is a sugar. This article gets into more detail in explaining what Diabetes and states,Muscle ...view middle of the document...

This form of Diabetes often appears at times of physical stress and during illness when the body produces additional glucose.In Type 2 Diabetes, the pancreas retains its ability to produce insulin, but either the quantity is inadequate for the body's needs, or insulin cannot be used to its full extent by the tissues. Most people who have this condition suffer from being overweight and require treatment, together with a strict weight-reducing diet and exercise program. It is said that 95% of people with Diabetes have Type 2. Some symptoms of Type 2 are frequent urinating, blurred vision, frequent infections (Lexi Comp).A genetic study done by researchers at the Joslin Diabetes Center and the Children's Hospital Boston Informatics Program, has discovered a group of genes that are involved in Type 2 Diabetes and shows that the activity of these genes changes even before diabetes develops, which is explained in the article "Type 2 diabetes linked to family of metabolic genes." The article describes these two genes, PCG1-alpha and PCG1-beta, that showed reduced activity not only in the people with Diabetes, but also in those with pre-Diabetes. This decreased in activity appeared to lead to reduced activity of a larger group of genes involved in the metabolism of fats and carbohydrates. These genes code for proteins in the mitochondria, cell structures that play an important role in energy metabolism. Reduced activity of these genes may cause an imbalance to increase insulin resistance, or an inability of the body's cells to use insulin properly, which is the first metabolic defect to Type 2 Diabetes.There has been a gene discovered that is a contributor to Type 1 Diabetes. The article "Genetic Mutation Found That Is Major Contributor to Type 1 Diabetes" states, "A natural mutation of a gene that helps regulate the reactivity of the immune system is a major contributor to type 1 diabetes, Medical College of Georgia researchers have found." It also states that by examining the transmission of genes from parents to children in nearly 1,000 diabetic families from around the world researchers found that a certain natural mutation of that SUMO-4 gene increases the risk of Type 1 Diabetes.Diabetes is not a genetically inherited disease. If your mother or father has Diabetes does not mean that you are going to get it. It just means that your risk of getting the disease is increased. You can over come getting Diabetes by maintaining a well-balanced diet and exercising.Part BDiabetes is a type of disease that can affect your whole lifestyle. There are so many adjustments that you have to make in order to live a healthy life. Some of these adjustments include changing your diet, eliminating harmful substance intake, and exercising regularly.From the Joslin Diabetes Center is an article posted about the feeling of fatigue from dealing with the disease. The article is entitled, "I Feel Burnt-Out by Diabetes Care. Any Suggestions About How to Get Back on Track?",...

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