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Biochemistry Essay

554 words - 3 pages

Biochemistry Task 3  



                                                                                                         (Hudon­Miller, Hemoglobin…, 2012) 

1.  Two differences between oxygenated and deoxygenated hemoglobin are shape and 
color. Color change is reflected in the amount of oxygen bound to the hemoglobin. The 
more oxygen there is, the brighter red the hemoglobin will be. In the oxygenated state the 
shape changes as well. In this state, the protein is in what is known as the R or relaxed 
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is possible to carry the sickle cell gene and not present with sickle cell anemia. In an 
individual who is a carrier of the gene, the normal red blood cells will dominate and the cells 
won’t sickle. An individual with sickle cell anemia has 2 recessive genes so there is no 
dominant gene to take over. In this scenario, as the diseased hemoglobin loses oxygen, it 
sickles, due to their sickled shape the red bloods will have a difficult time travelling through 
the bloodstream to get to the lungs to get oxygen. If these blood cells get stuck in the 
bloodstream, not only does it shorten their lifespan but they are unable to deliver oxygen 
efficiently throughout the body. (Hudon­Miller, Sickle…, 2012)  
4a.  Sickle cell is a recessive trait. With that being said, if you have 2 parents who are both 
carrying the trait there is a 25% chance of having a child with sickle cell anemia. The 
chance of having a child that is also a carrier is 50% and there is a 25% chance of having a 
child without the trait. (Hudon­Miller, Sickle…, 2012) 

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